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Preparative LC methods require  amassing fractionated eluent into discrete sample containers to isolate a number of analytes to be able to purify key elements or isolate impurities for additional investigations.This features is critical when reference requirements are unavailable for impurities and degradantsThe commonest refractive index detector

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correlations during the pharmaceutical products growth. Nevertheless, this kind of empirical dissolution designs have numerous inherent drawbacks [six, seven], which include that i) the elucidation in the underlying mass transport mechanisms is not possible; ii) not one characteristic parameter with the dosage sort is associated with the intrinsic

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